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"How Do Metabolic Issues Impact Performance for Athletes?"

Updated: Feb 21

Dehydration

Dehydration
Heat illness. (From Miller M et al: Sports medicine conditions: return to play: recognition, treatment, planning, 2013, LWW.)

Dehydration Overview


Fluid and Electrolyte Management

  • Loss of fluids and electrolytes impairs cardiovascular function and work capacity.

  • Solutions with low osmolarity (<10%) enhance absorption.

  • Suspect hyponatremia in individuals engaging in prolonged, intense exercise while consuming only water.

  • For exercises exceeding one hour, rehydration with fluids containing carbohydrates is advised, as this promotes sodium absorption.


Nutritional Supplements

  • Nutritional supplements remain contentious.

  • Creatine, a popular supplement, is known for increasing cellular water retention.

  • Using creatine during the competitive season may heighten the risk of dehydration and muscle cramps.


Ergogenic Drugs


Anabolic Steroids

  • These are testosterone derivatives misused by athletes to boost muscle mass, strength, and red blood cell production.

  • Known adverse effects include liver dysfunction, high cholesterol, cardiomyopathy, testicular shrinkage, increased blood clotting, fluid and electrolyte disturbances, gynecomastia, acne, mood swings (notably aggression), and permanent hair loss.

  • Heart disease risk is elevated due to higher LDL cholesterol and lower HDL cholesterol.

  • The International Olympic Committee standardizes urine sampling for detection.


Human Growth Hormone (HGH)

  • Produced using recombinant DNA techniques, HGH is commonly abused illegally to increase muscle size and weight, with side effects resembling those of steroids, including hypertension and gigantism.

  • Detection of HGH use is challenging.

  • Insulin-like growth factor-1 (IGF-1) shares similar effects with HGH.


Prohormones

  • Testosterone derivatives such as dehydroepiandrosterone (DHEA) and androstenedione are used as anabolic agents; however, their effects are debatable.


References


1. Miller, M. D., Thompson, S. R. Miller's Review of Orthopaedics, 8th Edition. Elsevier Enhanced Digital Version; 2019-11-08. Retrieved from vbk://97803236097912019-11-08.


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